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NEWSLETTER 6 (OCTOBER 2002)

 

SIXTH INTERNATIONAL CONFERENCE ON BIOTHERAPY

             The Sixth International Conference on Biotherapy will be held in the Congress Center of the Sivas Cumhuriyet University in Turkey on June 16-20, 2003. The main subjects of the Conference will be: maggot debridement therapy, apitherapy, hirudotherapy, ichthiotherapy, helminthotherapy, bacteriotherapy and biodiagnostics.

            The first, second and fourth IBS conferences were held in Porthcawl, South Wales, UK in 1996, 1997 and 1999, respectively, the third IBS conference in Jerusalem, Israel and the fifth in Wurzburg, Germany. We believe that all of them were extremely successful, and we plan to continue the tradition of exchanging information and ideas pertaining to the treatment of human diseases using living organisms such as fish, fly maggots, bees, leeches, helminthes and bacteria.

            The Sivas Cumhuriyet University is close to the Kangal Balikli Spa, which is a known place where ichthiotherapy is applied. The so called “doctor fish” such as  Cyprinion macrostomus macrostomus and Garra rufa obtusa may, by softening the psoriatic plague, clear away the scale and expose the lesion to water and sunlight. In addition people with neurological, rheumatic and skin diseases also visit this hot spring.

            At the Sixth International Conference on Biotherapy the clinical aspects of treatment with these organisms, as well as the scientific basis for their actions will be discussed.

            For more details see the section of “Conferences” in this website.

 

MDT IN TURKEY

            A study on the efficacy of maggot debridement therapy MDT for the treatment of chronic wounds has been lately started in Ankara, Turkey. The study has been initiated in the Gulhane Military Medical Academy (GMMA), Research and Development Center and approved by the Military Medical Academy-Local Ethic Committee. The aim of this study is to debride and heal necrotic and/or suppurative wounds in combination of MDT (using the larvae of the green-bottle fly, Lucilia sericata) and the hyperbaric oxygen method.

            A fly colony of Lucilia sericata is been maintained in the insectariums of the  Hacettepe University, Faculty of Science, Dept of Biology,  Section: Ecology in Ankara by Prof. Bülent Alten.  Sterile maggots are produced in the Medical Parasitology Division of GMMA.

The study group includes:

Assoc. Prof. Mehmet Tanyüksel, MD, Division of Medical Parasitology, GMMA, Ankara (PI)

Assist. Prof. Kadir Dündar, MD, Department of Undersea and Hyperbaric Medicine, GMMA, Ankara (Head, HBO)

Assist. Prof. Engin Araz, MD, PhD, Division of Medical Parasitology, GMMA, Ankara (co-researcher)

Assist. Prof. Bülent Alten, PhD, Ecology Section, Department of Biology, Faculty of Science, Hacettepe University, Ankara

Dr. Ayşegül Taylan Özkan, PhD, Parasitology Laboratory, Communicable Diseases Research Center, Refik Saydam National Institute of Health, Ankara (counselor)

Dr. Kosta Mumcuoğlu, PhD, Hebrew University, Hadassah School of Medicine, Department of Parasitology, Jerusalem, Israel (counselor)

 

HUMAN CANCER AND SNIFFER DOGS

By John Church

             Three remarkable cases of dogs recognizing human skin cancer have been reported in the UK.  These patients all had similar experiences.  They had a pet dog that demonstrated abnormal behavior, focused on the trouble spot.  This abnormal behavior caused their owners to seek medical advice, and have the lesions removed.  In each case the condition was found on histological examination to be an early cancer.  In each case the patient was not initially aware of the seriousness of their condition.

            Two of these cases were early malignant melanoma, a condition which if diagnosed late, will often by then have spread to other parts of the body, and go on to be fatal.  The third case was a basal cell carcinoma, generally a slower growing tumor, but which can cause serious problems, and if untreated ultimately be fatal.

            The first case to be reported was described in a letter to The Lancet, on  April 1st, 1989.  The second case was also described in The Lancet, on September 15th, 2001.  The third case was the most recently described, in the Sunday Telegraph of  September 23rd,  2001, but was actually chronologically the earliest, having occurred in the 1980s.

            In the past three months, due essentially to positive media attention to this phenomenon, six other patients have made contact with us, to tell us their stories.  All these stories have the common strand that a pet dog, enjoying a close bond with its owner, changed its behavior, causing the owner to seek medical advice, and have appropriate treatment for a cancer.  This full list now includes two further cases of malignant melanoma, two cases of carcinoma of the breast, one case of carcinoma of the cervix, and one a lymphoma with subcutaneous nodules.

            This is a plea to those who visit this site, and who might have personal knowledge of similar cases, to contact the International Biotherapy Society, with details.  We assume that there must have been similar cases out there somewhere, but because of the bizarre nature of the phenomenon, or for other reasons, have not yet been reported.

            Following the first description of a case, in April 1989, a group of doctors and dog trainers in the USA trained a dog to recognize malignant melanoma with an astonishing degree of success.  But this work has not progressed.  If a larger number of similar instances of this phenomenon could be gathered together, this would give considerable impetus to a formal study of this outstanding natural ability in dogs. This would be followed by the training of suitably chosen dogs to recognize a wide range of human diseases. Hopefully this would be at a stage before clinical diagnosis is clear, and to a level of specificity which out-performs diagnostic tests currently in clinical use.  Such dogs would be of great value in situations where medical services are scarce, or in emergency situations such as open tuberculosis in refugee camps, or outbreaks of serious disease such as Ebola fever.

 

References

Williams H, Pembroke A. Sniffer dogs in the melanoma clinic?  Lancet. April 1, 1989;1:734.

Jeffreys D. Amazing dog that sniffs out cancer.  Daily Mail (UK) April 22, 1997:45.

Church J, Williams H.  Another sniffer dog for the clinic?  Lancet Sept. 15, 2001;358:930.

Le Fanu J.  How sniffer-dogs border on the supernatural. The Sunday Telegraph Review (UK). September 23, 2001:4.

 


 

SNIFFER DOGS FOR THE EARLY DETECTION OF CANCER

 

  

            The concept of using dogs for the early detection of cancer is based on research conducted by Dr. Sydney Gordon (Battelle Labs), Dr. Jim Walker (Florida State University), and Dr. Michael Phillips (Menssana Research), who study gases exhaled in human breath. They have detected volatile chemicals in the breath of lung cancer patients, which are produced because tumor cells metabolize proteins differently than normal cells. These pathological metabolites have odors distinct from those of normal cells.

            The idea is to use professionally trained dogs for medical scent detection. Dogs have over 200 million scent-receiving cells in their nose, and are capable of detecting scent molecules at concentrations as low as 10 parts per quadrillion. This sensitivity allows dogs to detect the minute amounts of scent given off by tumor cells.

            In February 2001, researchers and clinicians from Pine Street were invited to attend a roundtable discussion at the Sensory Research Institute (Florida State University). At this meeting, research collaboration with James Walker, PhD, director of SRI, was established in order to study the early detection of cancer by using measurement devices to search for chemical markers of disease in the exhaled breath.

            The scientists are motivated by the need for early diagnosis in diseases such as lung cancer, breast cancer, liver cancer, melanoma, and heart disease. Early detection can reduce both morbidity and mortality due to these diseases. Furthermore, exhaled breath analysis is inexpensive and non-invasive, presenting minimal risk and negligible discomfort to research subjects.

             

BIODIAGNOSTICS WORKSHOP

By John Church

             A Workshop on Biodiagnostics (using sniffer-dog training for cancer detection) was held in October 5th, 2002, near London. Twenty-nine participants, including two of the patients described above patients whose dogs had alerted them to cancer, attended the workshop.  There were also representatives from dog training groups in California, Poland and the UK as well as physicians, including orthopedics, dermatologists and pathologists.  This unique gathering was an acclaimed success, and has generated considerable further interest in this phenomenon.  A fuller report will be added to this Website in due course.

 

APITHERAPY

 

Activity of the Apitherapy Commission of Apimondia
By Theodore Cherbuliez

August 31, 2002

             The Apitherapy Commission of Apimondia was elected in 1997. Its mission has two main parts:  first, developing Apitherapy as a medical science using the products of the honey bee hive in its fundamental and clinical aspects. This medical component includes de realization of finished products which, combined together with essential oils, represent an Api-pharmacopeia, and protocols of treatments that is an Api-medicine; secondly, implementing humanitarian projects as medical programs using Apitherapy in underprivileged countries.

            The Commission started its first project in Cuba in 1997. The humanitarian contributions of our programs include;

a)  Contribution to Cuba’s medicinal independence by using medicines that are­ or can be all produced in Cuba

b) Providing the well trained Cuban physicians with what they lacked most: medicines to carry out their art, available in sufficient quantity and in local currency

c) The fact that the principles proposed and material used are all supported by published scientific works

d)  Contribution to the country’s economical independence by the creation of jobs in a new apiculture for the production of medicinal products

e) Exploitation and valorization of forestry for the manufacture of essential oils and

f) To be in harmony with the Cuban spirit and values

            The program has several components:

1) Teaching: Three courses on Apitherapy were given in 1998, 1999 and 2000. The last one had 10 teachers, 235 health professional students from 65 institutions covering the whole of the island and nearly 200 of the students were awarded the diploma conferred by the Commission.  A fourth course, also with a faculty of 10, is planned for the middle of October 2002

2) Consultations in different hospitals and services

3) A clinical program.  In close collaboration with the head of the alternative medicine division of the Calixto Garcia University Hospital in Havana the Commission developed the first green medicine protocol for the treatment of a variety of diseases. Four formulas were developed: for the treatment of infections of broncho-pulmonary origin, of the gastro-intestinal track, of septicemias, and of skin abrasions, ulcers and burns.  With the approval of the Ministries of Health, Agriculture, Education and Planning more than 2,400 patients were treated (as of 2002 June) both as inpatients in hospitals and as outpatients in clinics. This approach was very well accepted by patients, yielded extremely favorable results, vastly superior to that of the control group and at a cost of a twentieth of the cost of commercial antibiotics purchased on the international markets

4) Development of a program of treatment of hospital acquired infections and of orthopedic infections at the Frank Pais Hospital for Orthopedic Surgery

5) Expansion of this Havana based activity to all 13 regions of Cuba

6) A proposal for the rational exploitation of forestry and construction of mobile distillation plants for the manufacture of medicinal grade essential oils

            This program has been declared of national interest by the government. In September1999 the Commission was invited by the Propolis Research Association of Japan to present papers on Apitherapy and on Bee Venom Therapy.

            In January 2000 the Commission produced a CD-ROM on Apitherapy. This opus includes 19 PowerPoint presentations on all subjects of Apitherapy, some 350 pages of information and is produced in three languages: English, French and Spanish. Versions in other languages are planned. It sells for 50 EUR or 45 USD.

            In June 2001 The Commission organized a three day course on Apitherapy at the University of Rabat, Medical School under the patronage of his Majesty the King of Morocco.

            In August 2001 the Commission was invited by the United Nation Development Program (UNDP) to Yaoundé, Burkina Faso, for a pre-feasibility study for a comprehensive Apitherapy program for the country. The presentation as very well received and began a dialogue between the Authorities and the Commission for the execution of such a project.

            In February 2002 the Commission was invited by the UNDP and the World Health Organization to do a presentation of the Commission’s program. The Authority’s interest was such that a feasibility study to be conducted by the Commission, with the collaboration of local experts, is scheduled for early 2003.

 

NEW PUBLICATIONS ON BIOTHERAPY

 A. MAGGOT DEBRIDEMENT THERAPY

B. APITHERAPY/BEE VENOM THERAPY

C. HIRUDOTHERAPY

D. BACTERIOTHERAPY

 

PROTOCOLS FOR MAINTENANCE OF LUCILIA SERICATA COLONY AND

STERILE MAGGOTS IN THE LABORATORY

 

By Kosta Y. Mumcuoglu

 

Department of Parasitology, Hebrew University-Hadassah Medical

School, P.O.Box 12272, Jerusalem 91120, Israel

 

A. FLY COLONY

B. COLLECTION AND STERILIZATION OF THE EGGS

C. PRODUCTION OF STERILE MAGGOTS

D. HARVESTING OF MAGGOTS FROM THE MEDIUM

E. MEDIA AND SOLUTIONS

F. CONSENT FORM FOR MDT (DRAFT)

G. PROTOCOL FOR FLY CAGES (DRAFT)



Copyright © 2007 Hebrew University, Jerusalem, Israel
Last modified: 01/01/07